Giganta
In her original origin, Giganta is an ape that is artificially-evolved into a giant red-headed woman to fight Wonder Woman. No kidding.
Lately Giganta has the ape-free origin of just being an ordinary woman who can grow super-tall and super-strong and fight Wonder Woman. I guess the "super-evolved gorilla" part makes a woman who can grow 50 feet tall too hard to believe...